Jeffrey Kohrt: search on Z-Library

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1

Psychological resilience and the gene regulatory impact of posttraumatic stress in Nepali child soldiers

Kohrt, Brandon A., Worthman, Carol M., Adhikari, Ramesh P., Luitel, Nagendra P., Arevalo, Jesusa M. G., Ma, Jeffrey, McCreath, Heather, Seeman, Teresa E., Crimmins, Eileen M., Cole, Steven W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 600 KB

english, 2016

2

Structure-based Drug Design of Pyrrolidine-1, 2-dicarboxamides as a Novel Series of Orally Bioavailable Factor Xa Inhibitors

Chad A. Van Huis, Christopher F. Bigge, Agustin Casimiro-Garcia, Wayne L. Cody, Danette A. Dudley, Kevin J. Filipski, Ronald J. Heemstra, Jeffrey T. Kohrt, Lakshmi S. Narasimhan, Robert P. Schaum, Erl

Journal:

Chemical Biology & Drug Design

Year:

2007

Language:

english

File:

PDF, 670 KB

english, 2007

3

Late-stage oxidative C(sp3)âH methylation

Feng, Kaibo, Quevedo, Raundi E., Kohrt, Jeffrey T., Oderinde, Martins S., Reilly, Usa, White, M. Christina

Journal:

Year:

2020

File:

PDF, 1.80 MB

2020

4

The discovery of glycine and related amino acid-based factor Xa inhibitors

Jeffrey T. Kohrt, Kevin J. Filipski, Wayne L. Cody, Christopher F. Bigge, Frances La, Kathleen Welch, Tawny Dahring, John W. Bryant, Daniele Leonard, Gary Bolton, Lakshmi Narasimhan, Erli Zhang, J. Th

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 551 KB

english, 2006

5

Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Powell, Noel A., Hoffman, Jennifer K., Ciske, Fred L., Kohrt, Jeffrey T., Baxi, Sangita M., Peng, Yun-Wen, Zhong, Min, Catana, Cornel, Ohren, Jeff, Perrin, Lisa A., Edmunds, Jeremy J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 372 KB

english, 2013

6

Cytotoxic T lymphocyte responses against melanocytes and melanoma

Gwendolen Y Chang, Holbrook E Kohrt, Tor B Stuge, Erich J Schwartz, Jeffrey S Weber, Peter P Lee

Journal:

Journal of Translational Medicine

Year:

2011

Language:

english

File:

PDF, 1.58 MB

english, 2011

7

Novel and selective spiroindoline-based inhibitors of sky kinase

Noel A. Powell, Jeffrey T. Kohrt, Kevin J. Filipski, Michael Kaufman, Derek Sheehan, Jeremy E. Edmunds, Amy Delaney, Yuli Wang, Francis Bourbonais, Doh-Yeel Lee, Frank Schwende, Fang Sun, Pat McConnel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 668 KB

english, 2012

8

Fluorodecarboxylation for the Synthesis of Trifluoromethyl Aryl Ethers

Zhang, Qing-Wei, Brusoe, Andrew T., Mascitti, Vincent, Hesp, Kevin D., Blakemore, David C., Kohrt, Jeffrey T., Hartwig, John F.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 741 KB

english, 2016

9

Demographic and Clinical Factors Associated with Non-Surgical Osteoarthritis Treatment Use Among Patients in Outpatient Clinics

Abbate, Lauren M., Jeffreys, Amy S., Coffman, Cynthia J., Schwartz, Todd A., Arbeeva, Liubov, Callahan, Leigh F., Negbenebor, Nicole A., Kohrt, Wendy M., Schwartz, Robert S., Vina, Ernest., Allen, Kel

Journal:

Arthritis Care & Research

Year:

2017

Language:

english

File:

PDF, 958 KB

english, 2017

10

ChemInform Abstract: Fluorodecarboxylation for the Synthesis of Trifluoromethyl Aryl Ethers.

Zhang, Qing-Wei, Brusoe, Andrew T., Mascitti, Vincent, Hesp, Kevin D., Blakemore, David C., Kohrt, Jeffrey T., Hartwig, John F.

Journal:

Year:

2016

File:

PDF, 21 KB

2016

11

Model Studies on the Synthesis of Hennoxazole A

Barrett, Anthony G. M., Kohrt, Jeffrey T.

Journal:

Year:

1995

File:

PDF, 165 KB

1995

12

The discovery of fluoropyridine-based inhibitors of the factor VIIa/TF complex—Part 2

Jeffrey T. Kohrt, Kevin J. Filipski, Wayne L. Cody, Cuiman Cai, Danette A. Dudley, Chad A. Van Huis, J. Adam Willardsen, Lakshmi S. Narasimhan, Erli Zhang, Stephen T. Rapundalo, Kamlai Saiya-Cork, Rob

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 235 KB

english, 2006

13

Activation of the G-Protein-Coupled Receptor 119: A Conformation-Based Hypothesis for Understanding Agonist Response

McClure, Kim F., Darout, Etzer, Guimarães, Cristiano R. W., DeNinno, Michael P., Mascitti, Vincent, Munchhof, Michael J., Robinson, Ralph P., Kohrt, Jeffrey, Harris, Anthony R., Moore, Dianna E.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.55 MB

english, 2011

14

Oxidative diversification of amino acids and peptides by small-molecule iron catalysis

Osberger, Thomas J., Rogness, Donald C., Kohrt, Jeffrey T., Stepan, Antonia F., White, M. Christina

Journal:

Year:

2016

Language:

english

File:

PDF, 555 KB

english, 2016

15

Rapid Assessment of Recognition Efficiency and Functional Capacity of Antigen-Specific T-Cell Responses

Kohrt, Holbrook E, Shu, Chen-Tsen, Stuge, Tor B, Holmes, Susan P, Weber, Jeffrey, Lee, Peter P

Journal:

Journal of Immunotherapy

Year:

2005

Language:

english

File:

PDF, 468 KB

english, 2005

16

Highly Functionalized Cyclohexenyl Systems: Enzymatic Resolution and Selective Oxirane Opening Reactions of p -Benzoquinone Derivatives

Kohrt, Jeffrey T., Gu, Jian-Xin, Johnson, Carl R.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 82 KB

english, 1998

17

Fluorodecarboxylation for the Synthesis of Trifluoromethyl Aryl Ethers

Zhang, Qing-Wei, Brusoe, Andrew T., Mascitti, Vincent, Hesp, Kevin D., Blakemore, David C., Kohrt, Jeffrey T., Hartwig, John F.

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 647 KB

english, 2016

18

Expedient synthesis of novel β-ketoesters from the Mizoroki–Heck coupling of ethyl 3-ethoxyacrylate with aryl and pyridyl halides

Kohrt, Jeffrey T., Conn, Ed, Maguire, Robert, Wright, Stephen W., Singer, Robert

Journal:

Tetrahedron Letters

Year:

2013

Language:

english

File:

PDF, 1.65 MB

english, 2013

19

A versatile copper-catalyzed coupling reaction of pyridin-2(1H)-ones with aryl halides

Kevin J. Filipski, Jeffrey T. Kohrt, Agustin Casimiro-Garcia, Chad A. Van Huis, Danette A. Dudley, Wayne L. Cody, Christopher F. Bigge, Shrilakshmi Desiraju, Shaoyi Sun, Samarendra N. Maiti, Mohamad R

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

20

A First-in-Human Phase 1 Study of Subcutaneous Outpatient Recombinant Human IL-15 (rhIL-15) in Adults with Advanced Solid Tumors

Miller, Jeffrey S, Morishima, Chihiro, McNeel, Douglas G., Patel, Manish R, Kohrt, Holbrook E., Thompson, John A, Sondel, Paul M., Wakelee, Heather A., Disis, Mary L., Kaiser, Judith C, Cheever, Marti

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 3.85 MB

english, 2017

21

Intrinsic Electrophilicity of a 4-Substituted-5-cyano-6-(2-methylpyridin-3-yloxy)pyrimidine Derivative: Structural Characterization of Glutathione Conjugates in Vitro

Kalgutkar, Amit S., Mascitti, Vincent, Sharma, Raman, Walker, Gregory W., Ryder, Tim, McDonald, Thomas S., Chen, Yue, Preville, Cathy, Basak, Arindrajit, McClure, Kim F., Kohrt, Jeffrey T., Robinson,

Journal:

Chemical Research in Toxicology

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

22

Pyrazole inhibitors of HMG-CoA reductase: An attempt to dramatically reduce synthetic complexity through minimal analog re-design

Scott D. Larsen, Toni-Jo Poel, Kevin J. Filipski, Jeffrey T. Kohrt, Jeffrey A. Pfefferkorn, Roderick J. Sorenson, Bradley D. Tait, Valerie Askew, Lisa Dillon, Jeffrey C. Hanselman, Gina H. Lu, Andrew

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 244 KB

english, 2007

23

Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Powell, Noel A., Hoffman, Jennifer K., Ciske, Fred L., Kaufman, Michael D., Kohrt, Jeffrey T., Quin, John, Sheehan, Derek J., Delaney, Amy, Baxi, Sangita M., Catana, Cornel, McConnell, Patrick, Ohren,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 3.10 MB

english, 2013

24

FUSED PYRAZOLE SYNTHESIS BY N-N BOND FORMATION: THE PYRAZOLO[5,1-b]BENZOTHIAZOLE SYSTEM

Bates, Dallas K., Kohrt, Jeffrey T., Folk, Heather, Xia, Mingde

Journal:

Heterocyclic Communications

Year:

1997

Language:

english

File:

PDF, 890 KB

english, 1997

25

Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor

McClure, Kim F., Jackson, Margaret, Cameron, Kimberly O., Kung, Daniel W., Perry, David A., Orr, Suvi T.M., Zhang, Yingxin, Kohrt, Jeffrey, Tu, Meihua, Gao, Hua, Fernando, Dilinie, Jones, Ryan, Erasga

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 735 KB

english, 2013

26

ChemInform Abstract: Expedient Synthesis of Novel β-Ketoesters from the Mizoroki-Heck Coupling of Ethyl 3-Ethoxyacrylate with Aryl and Pyridyl Halides.

Kohrt, Jeffrey T., Conn, Ed, Maguire, Robert, Wright, Stephen W., Singer, Robert

Journal:

Year:

2014

File:

PDF, 30 KB

2014

27

The Discovery of Fluoropyridine-Based Inhibitors of the Factor VIIa/TF Complex.

Jeffrey T. Kohrt, et al. et al.

Journal:

Year:

2006

File:

PDF, 29 KB

2006

28

The Discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an Orally Efficacious Factor Xa Inhibitor

Jeffrey T. Kohrt, Christopher F. Bigge, John W. Bryant, Agustin Casimiro-Garcia, Liguo Chi, Wayne L. Cody, Tawny Dahring, Danette A. Dudley, Kevin J. Filipski, Staci Haarer, Ron Heemstra, Nancy Janicz

Journal:

Chemical Biology & Drug Design

Year:

2007

Language:

english

File:

PDF, 922 KB

english, 2007

29

An efficient synthesis of 2-(3-(4-amidinophenylcarbamoyl)naphthalen-2-yl)-5-((2,2-methylpropyl)carbamoyl)benzoic acid: a factor VIIa inhibitor discovered by the Ono Pharmaceutical Company

Jeffrey T Kohrt, Kevin J Filipski, Stephen T Rapundalo, Wayne L Cody, Jeremy J Edmunds

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

30

Exploration of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides as potent, orally active Factor Xa inhibitors with extended duration of action

Chad A. Van Huis, Agustin Casimiro-Garcia, Christopher F. Bigge, Wayne L. Cody, Danette A. Dudley, Kevin J. Filipski, Ronald J. Heemstra, Jeffrey T. Kohrt, Robert J. Leadley Jr., Lakshmi S. Narasimhan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 682 KB

english, 2009

31

The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex

Jeffrey T. Kohrt, Kevin J. Filipski, Wayne L. Cody, Cuiman Cai, Danette A. Dudley, Chad A. Van Huis, J. Adam Willardsen, Stephen T. Rapundalo, Kamlai Saiya-Cork, Robert J. Leadley, Lakshmi Narasimhan,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 199 KB

english, 2005

32

Discovery of new piperidine amide triazolobenzodiazepinones as intestinal-selective CCK1 receptor agonists

Kimberly O. Cameron, Elena E. Beretta, Yue Chen, Margaret Chu-Moyer, Dilinie Fernando, Hua Gao, Jeffrey Kohrt, Sophie Lavergne, Paul Da Silva Jardine, Angel Guzman-Perez, Christopher Hoth, David A. Pe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 656 KB

english, 2012

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